1. Involvement of the Penta-EF-Hand Protein Pef1p in the Ca2+- ... - PLOS
Arrows indicate the critical calcium interacting residues E180, E181, and E248. ... Transition of Sar1p from the GTP-bound to the GDP-bound state was monitored by ...
Although it is well established that the coat protein complex II (COPII) mediates the transport of proteins and lipids from the endoplasmic reticulum (ER) to the Golgi apparatus, the regulation of the vesicular transport event and the mechanisms that act to counterbalance the vesicle flow between the ER and Golgi are poorly understood. In this study, we present data indicating that the penta-EF-hand Ca2+-binding protein Pef1p directly interacts with the COPII coat subunit Sec31p and regulates COPII assembly in Saccharomyces cerevisiae. ALG-2, a mammalian hom*olog of Pef1p, has been shown to interact with Sec31A in a Ca2+-dependent manner and to have a role in stabilizing the association of the Sec13/31 complex with the membrane. However, Pef1p displayed reversed Ca2+ dependence for Sec13/31p association; only the Ca2+-free form of Pef1p bound to the Sec13/31p complex. In addition, the influence on COPII coat assembly also appeared to be reversed; Pef1p binding acted as a kinetic inhibitor to delay Sec13/31p recruitment. Our results provide further evidence for a linkage between Ca2+-dependent signaling and ER-to-Golgi trafficking, but its mechanism of action in yeast seems to be different from the mechanism reported for its mammalian hom*olog ALG-2.
2. nama_10_gdp - Statistics | Eurostat - European Union
Bevat niet: e248 | Resultaten tonen met:e248
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3. Egypt attracts foreign investment as currency falls - Financial Times
22 mrt 2017 · Egypt is grappling with a budget deficit that reached 12.2 per cent of gross domestic product ... Domestic debt is high at 95 per cent of GDP. The ...
4. 2018 GDP figure revised down to 0.9% - Politics - Ansa.it
1 mrt 2019 · ISTAT said Friday that Italy's gross domestic product rose by 0.9% in 2018 after revised down its provisional estimate of 1% growth last ...
ISTAT said Friday that Italy's gross domestic product rose by 0.9% in 2018 after revised down its provisional estimate of 1% growth last year. The government put Italy's growth rate for 2018 at 1% in its forecasts late in December. (ANSA)
5. [PDF] Master Builders Australia Submission to the Senate Education and ...
5 feb 2021 · Represents about 11% of GDP, the second largest sector within the economy;. ▫. Trains more than one third of the total number of trades-based ...
6. A Rational Economic Model of Paygo Tax Rates
The distributions of labor and capital income are calculated from national data on real GDP, real wages and the real return to capital since 1950. With uniform ...
We argue that paygo rates are determined by a representative agent and a benevolent government jointly maximizing the expected life-time utility of the agent. The distributions of labor and capital in
7. [PDF] Egypt's IMF Program: Assessing the Political Economy Challenges
In order to help ease the adjustment process brought on by EFF reform, “[a]bout 1 percent of GDP in fiscal savings will be directed to additional food subsidies ...
8. [PDF] ANNUAL REPORT - Central Bank of Eswatini
E129.1 million in 2013 from E248.5 million recorded the previous year ... of GDP. Even though a supplementary budget of E318 million for 2013/14 was ...
9. Splitting the functions of Rim2, a mitochondrial iron/pyrimidine carrier
18 jan 2019 · Potential proton coupler E248, and contact residue K299 are indicated in red and blue respectively. ... GDP exchanger, which may also have some ...
Rim2 is an unusual mitochondrial carrier protein capable of transporting both iron and pyrimidine nucleotides. Here we characterize two point mutations generated in the predicted substrate-binding site, finding that they yield disparate effects on iron ...
10. UAE bankruptcy no longer leads straight to prison - Financial Times
22 mrt 2017 · The government's ambition is to boost the contribution of SMEs to GDP from 40 per cent now to 45 per cent in 2021. It hopes to foster 40,000 ...
11. [PDF] PDF - CDC
decreases in gross domestic product (GDP) resulting from poultry farming ... e248. 3. Zavala-Velasquez JE, Sosa-Ruiz JA, Zavala-Castro J, Jimenez ...
12. [PDF] NBAA President Ed Bolen Testimony, House TI Hearing, FAA ...
7 feb 2023 · gross domestic product. Considering the vast challenges facing ... 64(4):e245-e248. 11. Page 12. aiding employers in understanding the ...
13. multi0page.txt - World Bank Documents
... GDP Gross domestic product GNP Gross national product Kg Kilogram (2.2 ... E 248 207 159 . 74 125 worr] Mg eraso EconomcsDeatn, April 1 95 275 Portugal ...
* - - -s - ~~~~~~~-.H_ - -4 _s .__ . , wh k._ _ .. - _- , : - -_. t~~~~~~~~ - - ~- ' I '' J U . _1_ - . ,~~~~ b r-7 X~~~~~~~~~~~~~~~~~~~-Z!fw r- v - -- - Fs*5.. . - - - - -.V'., - : I -,- - t2~~~~~~~~~~~~~-i iL-~ ~~~~-~ -A-.~~~~~~~~~~ AVAILABLE NOW Social Indicators of Development 1995 Data This software edition of So- 0 n alows teuser to view and calIldicators of Develop- manipulate the data and to ment 1995 provides the exportdata selections toother same social and economic l C! k tt computer programs, such as indicators,formorethan200 _ Lotus 1-2-3, dBase, Javelin countries, as the print edi- Plus, and Aremos, and to tion. The 1995 edition fo- word-processing programs cuses on poverty indicators _ that read ASCII characters. that describe the character- istics of poverty and the effectiveness of efforts to The Social Indicators diskette set includes the reduce poverty. Unlike the print edition of the completei?STARS*softwareanddataondouble- Indicators, whichpresents dataforthreebroadtime density 3 1/2" diskettes for use on personal com- spans, the soft...
14. GDP, output and expenditures; changes, QNA, 1995- Q1 2024 - CBS
Bevat niet: e248 | Resultaten tonen met:e248
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15. Acc01967.1 (mRNA) Red5 | Kiwifruit Genome Database
Rab GDP dissociation inhibitor. Location, LG2 : 6475393 .. 6485513 (+) ... e-248. Identity = 419/444 (94.37%), Postives = 434/444 (97.75%), Query Frame ...
Overview
16. Expression of a Leishmania donovani nucleotide sugar transporter ... - OUCI
Ma, Golgi GDP-mannose uptake requires Leishmania LPG2. A member of a ... e248 https://doi.org/10.1371/journal.pntd.0000248; Zhang, Screening Leishmania ...
https://doi.org/10.1016/j.exppara.2011.09.010
17. RAS‐targeted cancer therapy: Advances in drugging specific ...
27 mei 2023 · ... GDP while promoting the dissociation of GDP from RAS. Then, GTP ... 2012;3(1):e248. [PMC free article] [PubMed] [Google Scholar]. 293 ...
Rat sarcoma (RAS), as a frequently mutated oncogene, has been studied as an attractive target for treating RAS‐driven cancers for over four decades. However, it is until the recent success of kirsten‐RAS (KRAS)[G12C] inhibitor that RAS ...
18. https://www.mdc-berlin.de/media/16725
... e-248 NA NA 0 A2AEW8;Q8VD04;A2AEW9;A2AEW5 A2AEW8;Q8VD04;A2AEW9;A2AEW5 25 ... GDP-GTP exchange factor subunit delta;Translation initiation factor eIF-2B ...
Protein.IDs Majority.Protein.IDs Peptide.Counts..all. Peptide.Counts..razor.unique. Peptide.Counts..unique. Protein.Names Uniprot Razor...unique.Peptides Unique.Peptides Peptides Razor...unique.Peptides.D_L4ctr_L0_280 Razor...unique.Peptides.S_L0ctr_L4_580 Sequence.Coverage.... Mol..Weight..kDa. Sequence.Length Experiment PEP Ratio.H.L Ratio.H.L.Normalized Intensity Reverse Contaminant A0ELI5;Q8K2D3;D3YYS4;D6RCX6 A0ELI5;Q8K2D3 5;5;1;1 5;5;1;1 5;5;1;1 Putative uncharacterized protein;Enhancer of mRNA-decapping protein 3;YjeF domain-containing protein 1 A0ELI5 5 5 1 2 0 14.6 55.957 508 2 1.7845e-08 NA NA 198470000 A0JNY3;Q8BUV3 A0JNY3;Q8BUV3 12;12 12;12 12;12 Gphn protein;Domain E;Domain G;Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase A0JNY3 12 12 2 3 2 19.2 83.665 772 4 4.7642e-82 0.78404 1.0635 809120000 A0MNP4;Q9ERF3;Q8BVQ0;F6U7Z8 A0MNP4;Q9ERF3;Q8BVQ0;F6U7Z8 6;6;6;5 6;6;6;5 6;6;6;5 CDW13/WDR61;WD repeat domain 61, isoform CRA_c;Meiotic recombination REC14 protein hom*olog;WD repeat-containing protein 61;Putative uncharacterized protein A0MNP4 6 6 2 1 2 35.7 33.772 305 6 2.1838e-85 0.70994 0.97035 235010000 A0PK78;Q78PG9 A0PK78;Q78PG9 6;6 6;6 6;6 Coiled-coil domain containing 25;Coiled-coil domain-containing protein 25 A0PK78 6 6 2 0 4 31.2 24.48 208 2 5.9107e-22 0.42715 0.58119 318090000 A1A4T2;Q8BHN3-2;Q8BHN3;Q8BHN3-3 A1A4T2;Q8BHN3-2;Q8BHN3 8;8;8;2 8;8;8;2 8;8;8;2 Alpha glucosidase 2 alpha neutral subunit;Alpha glucosidase 2 alph...
19. FAIR AND ACCURATE CREDIT TRANSACTIONS ACT OF 2003
243 Spriggs, William E........................................... 248 ... GDP. Since 1970, access to credit has greatly expanded as well. Thirty years ...
20. [PDF] D O D I S T R I T O F E D E R A L - SINJ-DF
Produtividade-GDP, instituída pela Lei n° 843, de 29 de dezembro de 1994 ... 215 e 248, da Lei n° 8.112, de 11 de dezembro 1990, e do § 5°, do artigo ...
